16.01.2017 WILEX AG  DE000A11QVV0

DGAP-Adhoc: WILEX AG: WILEX signs antibody license agreement with Telix Pharmaceuticals Limited


 
DGAP-Ad-hoc: WILEX AG / Key word(s): Alliance WILEX AG: WILEX signs antibody license agreement with Telix Pharmaceuticals Limited 16-Jan-2017 / 09:05 CET/CEST Disclosure of an inside information acc. to Article 17 MAR, transmitted by DGAP - a service of EQS Group AG. The issuer is solely responsible for the content of this announcement. --------------------------------------------------------------------------- Ad-hoc announcement Inside information according to Article 17 MAR WILEX signs antibody license agreement with Telix Pharmaceuticals Limited Munich, Germany, 16 January 2017 - WILEX AG (ISIN DE000A11QVV0 / WL6 / FSE) and Australian biopharmaceutical company Telix Pharmaceuticals Limited ("Telix"), today announced that they have concluded a worldwide license agreement for the development and commercialization of the imaging agent REDECTANE(R), a radiolabeled form of the monoclonal antibody Girentuximab. WILEX successfully completed a first Phase III trial with REDECTANE(R) in ccRCC. WILEX has granted Telix the worldwide licensing rights to further develop and commercialize the REDECTANE(R) molecular imaging program. Under the agreement, Telix will, as a first step, invest in an improved manufacturing process for the antibody. Under the terms of the agreement, WILEX is eligible to receive up-front and milestone payments totaling USD 3.7 million. In addition, WILEX is eligible to receive significant royalties on global net sales of REDECTANE(R), commensurate with a Phase III asset. Telix will be responsible for all development costs, as well as manufacturing and commercialization costs. Telix will also develop a therapeutic radioimmunoconjugate program based on Girentuximab. Early clinical data suggests that 177Lu-labeled Girentuximab has disease stabilizing effects in patients with advanced staged metastatic renal cancer. Telix is evaluating the use of CAIX targeting therapeutic agents with both beta- and alpha-emitting radionuclides for a variety of malignancies. Under the terms of the agreement, if a therapeutic product developed by Telix is ultimately granted marketing approval, WILEX will receive single-digit royalties. +++ End of the release +++ About REDECTANE(R) and the Phase III REDECT Study REDECTANE(R) (INN: 124I-Girentuximab) is a radiolabeled form of the monoclonal antibody Girentuximab, which binds to the Carbonic Anhydrase-9 (CAIX) antigen, expressed on the surface of cancer cells of the clear-cell phenotype. Accumulation of this antibody in tumor tissue can be visualized by means of molecular imaging using Positron Emission Tomography (PET). Additional anatomical information provided by computer tomography (CT) can be used to localize the accumulation of the antibody. REDECTANE(R) has the potential to fundamentally change therapy planning for renal cancer patients, including the avoidance of unnecessary surgery. Furthermore, REDECTANE(R) may also prove suitable for the diagnosis, staging and treatment response assessment in other kinds of cancers, such as lung and ovarian cancer. The Phase III REDECT trial demonstrated that REDECTANE(R) can differentiate between clear cell and non-clear cell renal cell cancer and that PET/CT molecular imaging with REDECTANE(R) was superior to CT alone. In order to obtain market authorization from the US Food and Drug Administration (FDA), REDECTANE(R) requires a second Phase III confirmatory study. WILEX has been granted a special protocol assessment (SPA) from the FDA for the planned confirmatory study (REDECT 2). About WILEX WILEX AG is a biopharmaceutical company based in Munich, Germany, that serves as a parent and holding company. The Company's research and development work is conducted by its subsidiary Heidelberg Pharma GmbH in Ladenburg. Heidelberg Pharma is the first company to develop the toxin Amanitin into cancer therapies using its proprietary Antibody Targeted Amanitin Conjugate (ATAC) technology and to advance the biological mode of action of the toxin as a novel therapeutic principle. This proprietary technology platform is being applied to develop the company's own therapeutic ATACs as well as in third-party collaborations to create a variety of ATAC candidates. The proprietary lead candidate is a BCMA ATAC for multiple myeloma. WILEX's clinical assets MESUPRON(R) and REDECTANE(R) have been partnered, while RENCAREX(R) is available for out-licensing and further development. WILEX is listed on the Frankfurt Stock Exchange: ISIN DE000A11QVV0 / WKN A11QVV / Symbol WL6. More information is available at http://www.wilex.com/.
Contact                           IR/PR-­support
WILEX AG                          MC Services AG
Sylvia Wimmer                     Katja Arnold (CIRO)
Corporate Communications          Managing Director & Partner
Tel.: +49 (0)89-41 31 38-29       Tel.: +49 (0)89-210 228-40
Email: investors[at]wilex.com     Mobile: +49 (0)160 9360 3022
Grillparzerstr. 18, 81675 Munich  Email: katja.arnold[at]mc-services.eu
This communication contains certain forward-looking statements relating to the Company's business, which can be identified by the use of forward- looking terminology such as "estimates", "believes", "expects", "may", "will" "should" "future", "potential" or similar expressions or by a general discussion of the Company's strategy, plans or intentions. Such forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause our actual results of operations, financial condition, performance, or achievements, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Given these uncertainties, prospective investors and partners are cautioned not to place undue reliance on such forward-looking statements. We disclaim any obligation to update any such forward-looking statements to reflect future events or developments. --------------------------------------------------------------------------- 16-Jan-2017 CET/CEST The DGAP Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases. Archive at www.dgap.de --------------------------------------------------------------------------- Language: English Company: WILEX AG Grillparzerstr. 18 81675 München Germany Phone: +49 (0)89 41 31 38 - 0 Fax: +49 (0)89 41 31 38 - 99 E-mail: [email protected] Internet: www.wilex.com ISIN: DE000A11QVV0 WKN: A11QVV Listed: Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Berlin, Dusseldorf, Munich, Stuttgart, Tradegate Exchange End of Announcement DGAP News Service --------------------------------------------------------------------------- 536523 16-Jan-2017 CET/CEST


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Umsatzerlöse1 1,90 3,67 7,31 8,49 1,75 18,51 9,86
EBITDA1,2 -10,35 -11,30 -9,60 -17,55 -24,83 -16,62 -20,33
EBITDA-Marge3 -544,74 -307,90 -131,33 -206,71 -1.418,86 -89,79
EBIT1,4 -10,75 -11,67 -10,14 -18,28 -25,63 -17,18 -21,21
EBIT-Marge5 -565,79 -317,98 -138,71 -215,31 -1.464,57 -92,82 -215,11
Jahresüberschuss1 -10,97 -11,67 -10,15 -18,37 -26,14 -19,70 -20,35
Netto-Marge6 -577,37 -317,98 -138,85 -216,37 -1.493,71 -106,43 -206,39
Cashflow1,7 -7,90 -9,98 -8,56 -17,89 -26,61 -8,57 -33,95
Ergebnis je Aktie8 -0,76 -0,41 -0,36 -0,61 -0,80 -0,44 -0,31
Dividende8 0,00 0,00 0,00 0,00 0,00 0,00 0,00
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1 in Mio. Euro; 2 EBITDA = Ergebnis vor Zinsen, Steuern und Abschreibungen; 3 EBITDA in Relation zum Umsatz; 4 EBIT = Ergebnis vor Zinsen und Steuern; 5 EBIT in Relation zum Umsatz; 6 Jahresüberschuss (-fehlbetrag) in Relation zum Umsatz; 7 Cashflow aus der gewöhnlichen Geschäftstätigkeit; 8 in Euro; Quelle: boersengefluester.de

Wirtschaftsprüfer: Deloitte

INVESTOR-INFORMATIONEN
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Heidelberg Pharma
WKN Kurs in € Einschätzung Börsenwert in Mio. €
A11QVV 3,070 Halten 143,08
KGV 2025e KGV 10Y-Ø BGFL-Ratio Shiller-KGV
0,00 0,00 0,00 -5,58
KBV KCV KUV EV/EBITDA
2,90 - 14,51 -5,18
Dividende '22 in € Dividende '23e in € Div.-Rendite '23e
in %
Hauptversammlung
0,00 0,00 0,00 20.06.2024
Q1-Zahlen Q2-Zahlen Q3-Zahlen Bilanz-PK
25.04.2024 11.07.2024 10.10.2024 25.03.2024
Abstand 60Tage-Linie Abstand 200Tage-Linie Performance YtD Performance 52 Wochen
-3,70% -7,00% -17,91% -34,40%
    
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Biotechnologie , A11QVV , HPHA , XETR:WL6